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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
11.5 DPC

15 matching records from 15 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Wnt7a  wingless-type MMTV integration site family, member 7A   (Synonyms: tw, Wnt-7a)
Results  Reference
1J:98369 Adamska M, Billi AC, Cheek S, Meisler MH, Genetic interaction between Wnt7a and Lrp6 during patterning of dorsal and posterior structures of the mouse limb. (Erratum: 2005; 233:1614). Dev Dyn. 2005 Jun;233(2):368-72
1J:73526 Ahn K, Mishina Y, Hanks MC, Behringer RR, Crenshaw EB 3rd, BMPR-IA signaling is required for the formation of the apical ectodermal ridge and dorsal-ventral patterning of the limb. Development. 2001 Nov;128(22):4449-61
1*J:306235 Allou L, Balzano S, Magg A, Quinodoz M, Royer-Bertrand B, Schopflin R, Chan WL, Speck-Martins CE, Carvalho DR, Farage L, Lourenco CM, Albuquerque R, Rajagopal S, Nampoothiri S, Campos-Xavier B, Chiesa C, Niel-Butschi F, Wittler L, Timmermann B, Spielmann M, Robson MI, Ringel A, Heinrich V, Cova G, Andrey G, Prada-Medina CA, Pescini-Gobert R, Unger S, Bonafe L, Grote P, Rivolta C, Mundlos S, Superti-Furga A, Non-coding deletions identify Maenli lncRNA as a limb-specific En1 regulator. Nature. 2021 Apr;592(7852):93-98
1*J:133600 Aoki M, Kiyonari H, Nakamura H, Okamoto H, R-spondin2 expression in the apical ectodermal ridge is essential for outgrowth and patterning in mouse limb development. Dev Growth Differ. 2008 Feb;50(2):85-95
1*J:165759 Chiu HS, Szucsik JC, Georgas KM, Jones JL, Rumballe BA, Tang D, Grimmond SM, Lewis AG, Aronow BJ, Lessard JL, Little MH, Comparative gene expression analysis of genital tubercle development reveals a putative appendicular Wnt7 network for the epidermal differentiation. Dev Biol. 2010 Aug 15;344(2):1071-87
1*J:45301 Cygan JA, Johnson RL, McMahon AP, Novel regulatory interactions revealed by studies of murine limb pattern in Wnt-7a and En-1 mutants. Development. 1997 Dec;124(24):5021-32
1J:327818 Murphy P, Armit C, Hill B, Venkataraman S, Frankel P, Baldock RA, Davidson DR, Integrated analysis of Wnt signalling system component gene expression. Development. 2022 Aug 15;149(16):dev200312
1J:144308 Ovchinnikov DA, Selever J, Wang Y, Chen YT, Mishina Y, Martin JF, Behringer RR, BMP receptor type IA in limb bud mesenchyme regulates distal outgrowth and patterning. Dev Biol. 2006 Jul 1;295(1):103-15
1*J:50461 Parr BA, Avery EJ, Cygan JA, McMahon AP, The classical mouse mutant postaxial hemimelia results from a mutation in the Wnt 7a gene. Dev Biol. 1998 Oct 15;202(2):228-34
1*J:23922 Parr BA, McMahon AP, Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb. Nature. 1995 Mar 23;374(6520):350-3
1*J:133947 Summerhurst K, Stark M, Sharpe J, Davidson D, Murphy P, 3D representation of Wnt and Frizzled gene expression patterns in the mouse embryo at embryonic day 11.5 (Ts19). Gene Expr Patterns. 2008 May;8(5):331-48
1J:52554 Vainio S, Heikkila M, Kispert A, Chin N, McMahon AP, Female development in mammals is regulated by Wnt-4 signalling. Nature. 1999 Feb 4;397(6718):405-9
1J:160731 Vivancos V, Chen P, Spassky N, Qian D, Dabdoub A, Kelley M, Studer M, Guthrie S, Wnt activity guides facial branchiomotor neuron migration, and involves the PCP pathway and JNK and ROCK kinases. Neural Dev. 2009;4:7
1*J:146657 Witte F, Dokas J, Neuendorf F, Mundlos S, Stricker S, Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation. Gene Expr Patterns. 2009 Apr;9(4):215-23
1J:184585 Yamamoto M, Matsuzaki T, Takahashi R, Adachi E, Maeda Y, Yamaguchi S, Kitayama H, Echizenya M, Morioka Y, Alexander DB, Yagi T, Itohara S, Nakamura T, Akiyama H, Noda M, The transformation suppressor gene Reck is required for postaxial patterning in mouse forelimbs. Biol Open. 2012;1(5):458-466

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory